Rare breast malignancy subtypes: A cytological, histological, and immunohistochemical correlation

Background: Breast malignancies encompass various subtypes which differ in their clinical presentations, outcomes, and response to the treatment regimens. Thus, a proper histological diagnosis and a special mention of the rare histologic subtypes are required to formulate clear recommendations of their treatment protocols. Materials and Methods: This is a 1-year retrospective study highlighting the rarely encountered subtypes on the mastectomy specimens received. Results: We encountered only 11 rare cases out of the total 153 mastectomy specimens received. The rare subtypes were as follows mucinous cystadenocarcinoma (0.6%), mucinous carcinoma (0.6%), dermatofibrosarcoma protuberans (0.6%), Squamous cell carcinoma (0.6%), papillary carcinoma (2.6%), medullary carcinoma (0.6%), and malignant mesenchymal tumor (1.3%). Conclusion: Our data suggest that these variants are distinct clinicopathological entities with a unique hormonal receptor status. Scant information is available on the rare breast tumor subtypes

Dermatofibrosarcoma Protuberans Of Breast - A Case Report

Dermatofibrosarcoma protuberans (DFSP) is best regarded as well differentiated, primary fibrosarcoma of skin. It is an uncommon, slow growing, locally aggressive, and reoccurring but rarely metastasizing tumor of the deep dermis and subcutaneous tissue. Clinically they present as firm solid nodules that arise most frequently on trunk and extremities. DFSP of the breast has been rarely reported. Here, we report a rare case of DFSP of the breast in 47-year-old woman.